Contributing Writer, Biopharmaceuticals & Open-Source Tools

Saskia de Vries

Leiden, Netherlands

Saskia covers process analytics in biopharmaceutical manufacturing for Spectrane, with particular interest in the open-source software ecosystem that has grown up around chemometric modelling and bioreactor monitoring. Her background is in biochemistry, with several years of bench-side experience in upstream cell-culture process development.

Articles by Saskia de Vries

Gold-nanostructured SERS substrate held at the inlet of a process flow cell

explainer

SERS in process analytics: when surface enhancement actually helps

SERS makes Raman a billion times stronger and a hundred times more fragile. For most inline measurements that is the wrong trade. The places where it pays off are narrow but real.

Saskia de Vries May 8, 2026

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Open-source chemometric libraries: what's actually usable in production

scikit-learn, pyChemometrics, ChemometricsLib, and the rest. A practitioner's review of what works for inline spectroscopy, what doesn't, and where the gaps still are.

Saskia de Vries Apr 30, 2026